Methylation of 3,4-Methylenedioxymethamphetamine in Formalin-Fixed Human Liver Tissue

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Methylation of 3,4-methylenedioxymethamphetamine in formalin-fixed human liver tissue.

3,4-Methylenedioxymethamphetamine (MDMA or ecstasy) is a commonly consumed recreational drug. As is the case with most secondary amines, MDMA reacts with formaldehyde under acidic conditions to form tertiary amines. This reaction is likely to occur in formalin-fixed tissue. In formalin solutions, MDMA is methylated producing 3,4-methylenedioxy-N,N-dimethylamphetamine (MDDA). MDDA standard was s...

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ژورنال

عنوان ژورنال: Journal of Analytical Toxicology

سال: 2005

ISSN: 0146-4760,1945-2403

DOI: 10.1093/jat/29.7.715